Our Double-stranded RNA (dsRNA) ELISA Kit is a highly sensitive and quantitative immunoassay developed based on the double-antibody sandwich ELISA platform. It enables accurate detection of dsRNA contaminants commonly present in in vitro transcribed (IVT) mRNA or mRNA vaccine formulations.

Residual dsRNA is an unwanted by-product during IVT synthesis and is known to trigger innate immune responses. Therefore, monitoring and minimizing dsRNA levels is essential for ensuring mRNA product quality, safety, and translational efficiency. This kit is specifically optimized for use in mRNA drug development, QC release testing, and process optimization, providing a robust tool for detecting trace levels of dsRNA in a variety of sample types.