ENDOTOXIN LEVEL <0.01 EU per 1 μg of the protein by the LAL method. Human Recombinant GMP Grade IL-15 (Interleukin-15). Interleukin-15 (IL-15) is a cytokine with structural similarity to Interleukin-2 (IL-2).
Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15
receptor beta chain (CD122) and the common gamma chain (gamma-C, CD132).
IL-15 is secreted by mononuclear phagocytes (and some other cells) following
infection by virus(es). This cytokine induces cell proliferation of natural killer cells; cells of the innate immune system whose principal role is to kill virally infected cells.
| Product Specifications | |
| Research Area | 2D-3D Cell Culture,Cell Therapy |
| Purity | >98% by SDS-PAGE |
| Target | IL-15 |
| Tested Applications | Cell Culture,Cell Therapy |
| Conjuation Label | His-Tag |
| Grade | GMP Grade |
| Physical Format | Lyophilized |
| Animal Free | Yes |
| Source(Natural/Synthetic) | Recombinant |
| Origin | E.coli |
| Sterile | Sterile |
| Animal Model | Human |
| Shipping Conditions | Blue Ice |
| Storage Conditions | Store at -20degC |
| Storage Buffer | 1X PBS-pH8.0 |
| UniProtKB | P40933 |
| Protein Type | Bioactive |
| Technical Notes | Protein Sequence - NWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVTESGCKECEELEEKNI KEFLQSFVHIVQMFINTSLE with polyhistidine tag at the N-terminus |
| Application Notes | BIOACTIVITY-Measure by its ability to induce MO7e human megakaryocytic leukemic proliferation. The ED50 for this effect is 0.5-3 ng/mL. The specific activity of recombinant Croyez GMP® human IL-15 is approximately 1.5 x 108 IU/mg. |
Human IL-15 (Interleukin-15) His-Tag GMP Grade Recombinant Protein
- Brand: Croyez
- Product Code: Croyez-C01017-GMP-100
- Availability: Pre-Order