Human Recombinant GMP Grade Activin A.
Activin and Inhibin are members of the TGF-beta superfamily of cytokines and are involved in a wide range of biological processes including tissue morphogenesis and repair, fibrosis, inflammation, neural development, hematopoiesis, reproductive system function, and carcinogenesis. Activin A is strongly expressed in wounded skin, and overexpression of Activin A in epidermis of transgenic mice improves wound healing and enhances scar formation. Activin A also regulates the morphogenesis of branching organs such as the prostate, lung, and kidney. There is also evidence showed that lack of Activin A during development results in neural developmental defects.
Product Specifications | |
Research Area | 2D-3D Cell Culture,Cell Therapy |
Purity | >98% by SDS-PAGE |
Target | Activin-A |
Tested Applications | Cell Culture,Cell Therapy |
Conjuation Label | His-Tag |
Grade | GMP Grade |
Physical Format | Lyophilized |
Animal Free | Yes |
Source(Natural/Synthetic) | Recombinant |
Origin | E.coli |
Sterile | Sterile |
Animal Model | Human |
Shipping Conditions | Blue Ice |
Storage Conditions | Store at -20degC |
Storage Buffer | 1X PBS-pH8.0 |
UniProtKB | P08476 |
Protein Type | Bioactive |
Technical Notes | ENDOTOXIN LEVEL <0.1 EU per 1 μg of the protein by the LAL method. |
Application Notes | BIOACTIVITY-Measure by its ability to induce hemoglobin expression in K562 cells. The ED50 for this effect is <0.85 ng/mL. The specific activity of recombinant human Activin A is approximately >1.4 x 103 IU/mg. |
Human Activin A His-Tag GMP Grade Recombinant Protein
- Brand: Croyez
- Product Code: Croyez-C01119-GMP-1000
- Availability: Pre-Order