Human Recombinant GMP Grade TNF alpha (Tumor necrosis factor alpha).
Tumor necrosis factor alpha (TNF alpha) is a kind of pleiotropic pro-inflammatory cytokine. It is secreted by various cells, such as adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. Proteolysis of the integral membrane precursor form of TNF alpha from cells soluble can release homotrimeric TNF alpha. TNF alpha can bind with some TNF alpha receptors induces apoptosis, besides, also trigger other responses depending on cell type, receptor expression, and signal transduction status. TNF alpha participate in the inflammatory response.
| Product Specifications | |
| Research Area | 2D-3D Cell Culture,Cell Therapy |
| Purity | >98% by SDS-PAGE |
| Target | TNFa |
| Tested Applications | Cell Culture,Cell Therapy |
| Conjuation Label | His-Tag |
| Grade | GMP Grade |
| Physical Format | Lyophilized |
| Animal Free | Yes |
| Source(Natural/Synthetic) | Recombinant |
| Origin | E.coli |
| Sterile | Sterile |
| Animal Model | Human |
| Shipping Conditions | Blue Ice |
| Storage Conditions | Store at -20degC |
| Storage Buffer | 1X PBS-pH8.0 |
| UniProtKB | P01375 |
| Protein Type | Bioactive |
| Technical Notes | ENDOTOXIN LEVEL <0.1 EU per 1 μg of the protein by the LAL method. |
| Application Notes | BIOACTIVITY-Measure by its ability to induce cytotoxicity in L929 cells in the presence of actinomycin D. The ED50 for this effect is <0.2 pg/mL. The specific activity of recombinant human TNF alpha is approximately >9 x 109 IU/mg. |
Human TNF alpha (Tumor necrosis factor alpha) His-Tag GMP Grade Recombinant Protein
- Brand: Croyez
- Product Code: Croyez-C01047-GMP-1000
- Availability: Pre-Order