ENDOTOXIN LEVEL <0.01 EU per 1 μg of the protein by the LAL method. Human Recombinant GMP Grade IL-2 (Interleukin-2). Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5-16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 is part of the body's natural response to microbial infection, and in discriminating between foreign ("non-self") and "self". IL-2 mediates its effects by binding to IL-2 receptors, which are expressed by lymphocytes.
| Product Specifications | |
| Research Area | 2D-3D Cell Culture,Cell Therapy |
| Purity | >98% by SDS-PAGE |
| Target | IL-2 |
| Tested Applications | Cell Culture,Cell Therapy |
| Conjuation Label | His-Tag |
| Grade | GMP Grade |
| Physical Format | Lyophilized |
| Animal Free | Yes |
| Source(Natural/Synthetic) | Recombinant |
| Origin | E.coli |
| Sterile | Sterile |
| Animal Model | Human |
| Shipping Conditions | Blue Ice |
| Storage Conditions | Store at -20degC |
| Storage Buffer | 1X PBS-pH8.0 |
| UniProtKB | P60568 |
| Protein Type | Bioactive |
| Technical Notes | Protein Sequence - MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVL ELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT with polyhistidine tag at the C-terminus |
| Application Notes | BIOACTIVITY-Measure by its ability to induce proliferation in CTLL-2 cells. The ED50 for this effect is <0.2 ng/mL. The specific activity of recombinant human IL-2 is approximately >2.5 x 107 IU/mg. Measure by its ability to induce proliferation in NK cells. The ED50 for this effect is <46 ng/mL. |
Human IL-2 (Interleukin-2) His-Tag GMP Grade Recombinant Protein
- Brand: Croyez
- Product Code: Croyez-C01004-GMP-100
- Availability: Pre-Order