ENDOTOXIN LEVEL <0.1 EU per 1 μg of the protein by the LAL method. Human Recombinant GMP Grade IL-4 (Interleukin-4). The interleukin-4 (IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4 in a positive feedback loop. The cell that initially produces IL-4, thus inducing Th2 differentiation, has not been identified, but recent studies suggest that basophils may be the effector cell. It is closely related and has functions similar to IL-13.
| Product Specifications | |
| Research Area | 2D-3D Cell Culture,Cell Therapy |
| Purity | >98% by SDS-PAGE |
| Target | IL-4 |
| Tested Applications | Cell Culture,Cell Therapy |
| Conjuation Label | His-Tag |
| Grade | GMP Grade |
| Physical Format | Lyophilized |
| Animal Free | Yes |
| Source(Natural/Synthetic) | Recombinant |
| Origin | E.coli |
| Sterile | Sterile |
| Animal Model | Human |
| Shipping Conditions | Blue Ice |
| Storage Conditions | Store at -20degC |
| Storage Buffer | 1X PBS-pH8.0 |
| UniProtKB | P05112 |
| Protein Type | Bioactive |
| Technical Notes | Protein Sequence - MHKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGL AGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS with polyhistidine tag at the C-terminus |
| Application Notes | BIOACTIVITY-Measure by its ability to induce TF-1 cells proliferation. The ED50 for this effect is <0.2 ng/mL. The specific activity of recombinant human IL-4 is approximately >2.8 x 107 IU/mg. |
Human IL-4 (Interleukin-4) His-Tag GMP Grade Recombinant Protein
- Brand: Croyez
- Product Code: Croyez-C01006-GMP-1000
- Availability: Pre-Order