The human free, soluble, uncomplexed RANKL (TNFSF11) high sensitvity Sandwich ELISA kit is intended for the quantitative measurement of sRANKL levels in serum and heparin plama samples.
The free sRANKL ELISA is highly recognised with >300 publications to date.
Target Information: RANKL, the receptor activator of nuclear factor kappa B ligand, a member of the tumor necrosis factor (TNF) family, is the main stimulatory factor for the formation of mature osteoclasts and is essential for their survival. RANKL activates its specific receptor RANK, located on osteoclasts and dendritic cells. RANKL and its specific receptor RANK are not only key regulators of bone remodeling but also play an essential role in immunobiology, e.g. lymph node formation, establishment of the thymic microenviroment, mammary gland development during pregnancy, bone metastasis in cancer and sex-hormone, progestin-driven breast cancer, thermoregulation, and finally in the development of type 2 diabetes mellitus.
| Product Specifications | |
| Research Area | Bone Metabolism |
| Assay Type | ELISA Kit |
| Reactive Species | Human |
| Target | free sRANKL |
| Sample Types | Serum,Plasma |
| Shipping Conditions | Blue Ice |
| Storage Conditions | 2-8 deg.C |
| Sensitivity | 0.2 pg/ml (=0.01 pmol/l) |
| Assay Time | overnight assay |
| Percision CV% | intra-assay: 4%, inter-assay: 3% |
| Molecular Weight | 20 kDa |
| Detection Method | ELISA |
| Assay Range | 1.25-40 pg/ml (0.0625-2 pmol/l) |
| Regulatory Information | RUO |
| Technical Notes | Precision(intra-assay: 4%, inter-assay: 3%) |
| Application Notes | Sample Vol :150µl/well |
| Articles & Publications | Widely cited and certified; references available upon request. |
Human FREE soluble RANKL ELISA
- Brand: BMG
- Product Code: BMG-BI-20462
- Availability: Pre-Order