The human DKK-1 (Dickkopf-1) Sandwich ELISA (enzyme-linked immunosorbent assay) kit is a quick day test that is intended for the quantitative direct measurement of DKK-1 levels in human serum samples.
This human DKK-1 ELISA is highly recognised with >180 references to date.
Target Information: Dickkopf-1 (DKK-1) is a 28.67 kDa secreted protein that acts as soluble inhibitor of the Wnt signalling pathway. This pathway contains lipid-modified glycoproteins that activate cell surface receptor-mediated signal transduction to regulate cell activities like: cell fate, proliferation, migration, polarity, and gene expression. DKK-1 regulates developmental processes of all kinds. Thus, DKK-1 is also involved in the regulation of bone metabolism as it effects osteoblast differentiation and in regulation of tumourgenetic activity.
| Product Specifications | |
| Research Area | Bone Metabolism,Cardiovascular |
| Assay Type | ELISA Kit |
| Reactive Species | Human |
| Target | Dickkopf-1 |
| Sample Types | Serum |
| Shipping Conditions | Blue Ice |
| Storage Conditions | 2-8 deg.C |
| Sensitivity | 43 pg/ml (=1.7 pmol/l) |
| Assay Time | 3.5 hrs |
| Percision CV% | intra-assay: 3%, inter-assay: 3% |
| Molecular Weight | 25.8 kDa |
| Detection Method | ELISA |
| Assay Range | 256.38-4102 pg/ml (=10-160 pmol/l) |
| Regulatory Information | RUO |
| Technical Notes | Precision(intra-assay: 3%, inter-assay: 3%) |
| Application Notes | Sample Vol :20µl/well |
| Articles & Publications | Widely cited and certified; references available upon request. |
Tags: DKK-1, Dickkopf-1, Wnt