Human Recombinant GMP Grade IL-3
Interleukin-3 (IL-3) is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. It acts by binding to the IL-3 receptor. IL-3 stimulates the differentiation of multipotent hematopoietic stem cells into myeloid progenitor cells or, with the addition of IL-7, into lymphoid progenitor cells. In addition, IL-3 stimulates proliferation of all cells in the myeloid lineage (granulocytes, monocytes, and dendritic cells), in conjunction with other cytokines, e.g., Erythropoietin (EPO), Granulocyte macrophage colony-stimulating factor (GM-CSF), and IL-6. It is secreted by basophils and activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response.
Product Specifications | |
Research Area | 2D-3D Cell Culture,Cell Therapy |
Purity | >98% by SDS-PAGE |
Target | IL-3 |
Tested Applications | Cell Culture,Cell Therapy |
Conjuation Label | His-Tag |
Grade | GMP Grade |
Physical Format | Lyophilized |
Animal Free | Yes |
Source(Natural/Synthetic) | Recombinant |
Origin | E.coli |
Sterile | Sterile |
Animal Model | Human |
Shipping Conditions | Blue Ice |
Storage Conditions | Store at -20degC |
Storage Buffer | 1X PBS-pH8.0 |
UniProtKB | P08700 |
Protein Type | Bioactive |
Technical Notes | ENDOTOXIN LEVEL <0.1 EU per 1 μg of the protein by the LAL method. |
Application Notes | BIOACTIVITY-Measure by its ability to induce TF-1 cells proliferation. The ED50 for this effect is <0.15 ng/mL. The specific activity of recombinant human IL-3 is approximately >1.2 x 106 IU/mg. |
Human IL-3 (Interleukin-3) His-Tag GMP Grade Recombinant Protein
- Brand: Croyez
- Product Code: Croyez-C01005-GMP-100
- Availability: Pre-Order
Available Options
Tags: IL3, IL-3, interleukin_3