ENDOTOXIN LEVEL <0.1 EU per 1 μg of the protein by the LAL method. Human Recombinant GMP Grade Flt-3 Ligand (Fms-related tyrosine kinase 3 ligand). Fms-related tyrosine kinase-3 ligand (Flt-3 Ligand) is a protein which in humans is encoded by the FLT3LG gene. Flt-3 ligand has a tyrosine-protein kinase activity & a growth factor that stimulate the proliferation of hematopoietic progenitor cells of both lymphoid and myeloid origin. Flt3-Ligand synergizes with other CSFs and interleukins to induce growth and differentiation.
| Product Specifications | |
| Research Area | 2D-3D Cell Culture,Cell Therapy |
| Purity | >98% by SDS-PAGE |
| Target | FLT-3 |
| Tested Applications | Cell Culture,Cell Therapy |
| Conjuation Label | His-Tag |
| Grade | GMP Grade |
| Physical Format | Lyophilized |
| Animal Free | Yes |
| Source(Natural/Synthetic) | Recombinant |
| Origin | E.coli |
| Sterile | Sterile |
| Animal Model | Human |
| Shipping Conditions | Blue Ice |
| Storage Conditions | Store at -20degC |
| Storage Buffer | 1X PBS-pH8.0 |
| UniProtKB | P49771 |
| Protein Type | Bioactive |
| Technical Notes | Protein Sequence - MTQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTVASNLQDEELCGGLWRLVLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPP PSCLRFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLPPPWSPRPLEATAPTA with polyhistidine tag at the C-terminus |
| Application Notes | BIOACTIVITY-Measure by its ability to induce proliferation in BaF3 cells transfected with mouse Flt-3. The ED50 for this effect is <0.8 ng/mL. The specific activity of recombinant human Flt-3 Ligand is > 1.5 x 106 IU/mg. |
Human Flt-3 Ligand (Fms-related tyrosine kinase 3 ligand) His-Tag GMP Grade Recombinant Protein
- Brand: Croyez
- Product Code: Croyez-C01085-GMP-1000
- Availability: Pre-Order